113 Results for "

Polygonum chinense Linn.

" in MedChemExpress (MCE) Product Catalog:
Products (113)

113 Results for "Polygonum chinense Linn." in MCE Product Catalog:

53
Silvestrol
Silvestrol
0 Images
53 Publications Verification
Cat. No.: HY-13251
CAS No.: 697235-38-4
Purity:  99.96%
Synonyms: (-)-Silvestrol
Category:  

Agave americana Linn. Natural Products Agavaceae Plants Disease Research Fields Cancer

Target:  

Eukaryotic Initiation Factor (eIF) Apoptosis Autophagy

Silvestrol is a eukaryotic translation initiation factor 4A (eIF4A) inhibitor isolated from Agave americana Linn.. Silvestrol induces autophagy and caspase-mediated apoptosis .
14
Morusin
Morusin
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14 Cited Publications
Cat. No.: HY-N0622
CAS No.: 62596-29-6
Synonyms: Mulberrochromene
Category:  

Infection other families Flavonoids Anti-aging Flavones Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

NF-κB STAT Bacterial

Morusin is a prenylated flavonoid isolated from Morus alba Linn. with various biological activities, such as antitumor, antioxidant, and anti-bacteria property. Morusin could inhibit NF-κB and STAT3 activity.
12
Vitexin
Vitexin
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12 Cited Publications
Cat. No.: HY-N0013
CAS No.: 3681-93-4
Category:  

Cardiovascular Disease Neurological Disease Anti-aging Flavones Metabolic Disease Plants Flavonoids Leguminosae Phenols Polyphenols Disease Research Fields Trigonella foenum-graecum Linn. Cancer

Target:  

Autophagy

Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects .
11
Hematoxylin
Hematoxylin
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11 Cited Publications
Cat. No.: HY-N0116
CAS No.: 517-28-2
Synonyms: Natural Black 1; Haematoxylin
Category:  

Leguminosae Caesalpinia sappan L. Other Diseases Phenols Polyphenols Plants Disease Research Fields

Target:  

Amyloid-β

Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC50 of 1.6 μM.
10
Isobavachalcone
Isobavachalcone
0 Images
10 Cited Publications
Cat. No.: HY-13065
CAS No.: 20784-50-3
Purity:  99.01%
Synonyms: Corylifolinin; Isobacachalcone
Category:  

Flavonoids Chalcones Leguminosae Phenols Polyphenols Psoralea corylifolia L. Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer

Target:  

Akt Reactive Oxygen Species (ROS) Apoptosis Autophagy

Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity .
7
Juglanin
Juglanin
0 Images
7 Cited Publications
Cat. No.: HY-N3442
CAS No.: 5041-67-8
Category:  

Flavonols other families Flavonoids Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

JNK Apoptosis Autophagy

Juglanin, a occurring flavonoid that can be isolated from crude Polygonum aviculare, is a JNK acticator, with anti-inflammatory, anti-oxidant and anti-tumor activities. Juglanin can induce apoptosis and autophagy on human breast cancer cells .
5
Saikosaponin A
Saikosaponin A
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5 Cited Publications
Cat. No.: HY-N0246
CAS No.: 20736-09-8
Category:  

Triterpenes Terpenoids Plants Umbelliferae Disease Research Fields Cancer Carphephorus corymbosus (Nutt.) Torr. & A.Gray

Target:  

LXR Bacterial

Saikosaponin A is the main active ingredient in Bupleurum chinense, which can regulate lipid metabolism and promote cholesterol efflux in early atherosclerosis. In addition, Saikosaponin A may also serve as a potential peroxisome proliferator-activated receptor γ (PPAR-γ) agonist, significantly promoting the expression of PPAR-γ. Saikosaponin A can be used in the study of hyperlipidemic pancreatitis .
4
Asparagusic acid
Asparagusic acid
0 Images
4 Cited Publications
Cat. No.: HY-50730
CAS No.: 2224-02-4
Category:  

Infection Liliaceae Ketones, Aldehydes, Acids Plants Disease Research Fields Asparagus officinalis L.

Target:  

Parasite Endogenous Metabolite

Asparagusic acid is a sulfur-containing flavor component produced by Asparagus officinalis Linn., with anti-parasitic effect. Asparagusic acid is a plant growth inhibitor .
2
Methyl vanillate
Methyl vanillate
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2 Cited Publications
Cat. No.: HY-75342
CAS No.: 3943-74-6
Category:  

Microorganisms Monophenols Oryza sativa Linn. Gramineae Phenols Plants

Target:  

Wnt Reactive Oxygen Species (ROS) Endogenous Metabolite

Methyl vanillate, one of the ingredients in Oryza sativa Linn., is a Wnt/β-catenin pathway activator . A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.
2
Moracin O
Moracin O
0 Images
2 Cited Publications
Cat. No.: HY-N3244
CAS No.: 123702-97-6
Category:  

Neurological Disease Phenols Polyphenols Plants Moraceae Disease Research Fields Inflammation/Immunology Morus alba Linn.

Target:  

HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS)

Moracin O is a 2-arylbenzofuran isolated from the Morus alba Linn. . Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin O reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin O has neuroprotective and anti-inflammatory effects .
1
Kukoamine A
Kukoamine A
0 Images
1 Cited Publications
Cat. No.: HY-N2392
CAS No.: 75288-96-9
Category:  

Cardiovascular Disease Alkaloids other families Other Alkaloids Phenols Polyphenols Plants Disease Research Fields

Target:  

Parasite Lipoxygenase Opioid Receptor Apoptosis Autophagy Reactive Oxygen Species (ROS) Interleukin Related TNF Receptor PGE synthase COX

Kukoamine A, a spermine alkaloid, is an orally active and brain-penetrant component found in the root barks of Lycium chinense (L. chinense) Miller. Kukoamine A inhibits purified Crithidia fasciculata trypanothione reductase and soybean lipoxygenase, activates μ-opioid receptor. Kukoamine A can inhibt cancer cell proliferation, migration and invasion, cause G0/G1 phase cell cycle arrest and induce apoptosis. Kukoamine A exerts neuroprotective effect and can induce autophagy . Kukoamine A inhibits LPS (HY-D1056)-induced NO, ROS, PGE2, TNF-α, IL-1β, IL-6 production and COX-2 activity. Kukoamine A reverses palmitic acid-induced insulin resistance, lipid accumulation, and oxidative stress via downregulation of Srebp-1c. Kukoamine A can be used for the research of cancer, infection, inflammation, metabolic and neurological disease, such as glioblastoma and Parkinson's disease .
1
Arnidiol
Arnidiol
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1 Cited Publications
Cat. No.: HY-N4165
CAS No.: 6750-30-7
Category:  

Triterpenes Terpenoids Dendranthema morifolium (Ramat.) Tzvel. Other Diseases Plants Compositae Disease Research Fields

Target:  

Others

Arnidiol is a pentacyclic triterpene isolated from Barleria Longiflora Linn F. .
1
Emodin-1-O-β-D-glucopyranoside
Emodin-1-O-β-D-glucopyranoside
0 Images
1 Cited Publications
Cat. No.: HY-N2394
CAS No.: 38840-23-2
Category:  

Quinones Rheum palmatum L. Polygonaceae Anthraquinones Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Bacterial

Emodin-1-O-β-D-glucopyranoside, isolated from medicinal plant Polygonum cuspidatum Sieb. & Zucc, is a potent and noncompetitive bacterial neuraminidase (BNA) inhibitor with an IC50 of 0.85 μM .
1
3-Epioleanolic acid
3-Epioleanolic acid
0 Images
1 Cited Publications
Cat. No.: HY-N4290
CAS No.: 25499-90-5
Category:  

Triterpenes other families Terpenoids Plants Disease Research Fields Inflammation/Immunology

Target:  

Others

3-Epioleanolic acid is an active component of Verbena officinalis Linn, with anti-inflammatory activity .
1
Saikogenin D
Saikogenin D
0 Images
1 Cited Publications
Cat. No.: HY-N4237
CAS No.: 5573-16-0
Category:  

Triterpenes Terpenoids Plants Umbelliferae Disease Research Fields Inflammation/Immunology Carphephorus corymbosus (Nutt.) Torr. & A.Gray

Target:  

Prostaglandin Receptor Potassium Channel

Saikogenin D is isolated from?Bupleurum chinense, has anti-inflammatory effects. Saikogenin D activates epoxygenases that converts arachidonic acid to epoxyeicosanoids and dihydroxyeicosatrienoic acids, and the metabolites secondarily inhibit prostaglandin E2 (PGE2) production. Saikogenin D results in an elevation of [Ca 2+]i due to Ca 2+ release from intracellular stores .
1
Vanicoside A
Vanicoside A
0 Images
1 Cited Publications
Cat. No.: HY-N11003
CAS No.: 155179-22-9
Category:  

Polygonaceae Phenols Polyphenols Plants Persicaria orientalis (L.) Spach

Target:  

PKC Reactive Oxygen Species (ROS)

Vanicoside A is a phenylpropanoid glycoside. Vanicoside A can be isolated from Polygonum pensylvanicum. Vanicoside A inhibits protein kinase C (PKC), induces substantial ROS production. Vanicoside A exhibits anticancer activity against melanoma .
1
Vitexin (Standard)
Vitexin (Standard)
0 Images
1 Cited Publications
Cat. No.: HY-N0013R
CAS No.: 3681-93-4
Category:  

Flavonoids Leguminosae Flavones Phenols Polyphenols Plants Trigonella foenum-graecum Linn.

Target:  

Reference Standards Autophagy

Vitexin (Standard) is the analytical standard of Vitexin. This product is intended for research and analytical applications. Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects .
Protodioscin
Protodioscin
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Cat. No.: HY-N0799
CAS No.: 55056-80-9
Category:  

Leguminosae Plants Endogenous metabolite Disease Research Fields Trigonella foenum-graecum Linn. Cancer Steroids

Target:  

Endogenous Metabolite

Protodioscin, a major steroidal saponin in Trigonella foenum-graecum Linn., has been shown to exhibit multiple biological actions, such as anti-hyperlipidemia, anti-cancer, sexual effects and cardiovascular properties.
Dalbergin
Dalbergin
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Cat. No.: HY-N8347
CAS No.: 482-83-7
Category:  

Dalbergia odorifera T. Chen Monophenols Leguminosae Other Diseases Coumarins Phenols Phenylpropanoids Plants Disease Research Fields

Target:  

Apoptosis

Dalbergin is a composition of the extract from the Dalbergia Sissoo Linn. knot wood. Dalbergin demonstrats notable antioxidant ability .
(E/Z)-Polydatin
(E/Z)-Polydatin
0 Images
Cat. No.: HY-N0120
CAS No.: 65914-17-2
Synonyms: (E/Z)-Piceid
Category:  

Stilbenes Polygonaceae Reynoutria japonica Houtt. Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Drug Isomer

(E/Z)-Polydatin ((E/Z)-Piceid) is a mixture of the E/Z configurations of Polydatin (HY-N0120A). Polydatin can be isolated from Polygonum cuspidatum, grapes, peanuts, red wine, hop pellets, cocoa-containing products and chocolate products. Polydatin exhibits multiple biological properties, such as anti-platelet aggregation, anti-low-density lipoprotein oxidation, cardioprotective activity, anti-inflammatory and immunomodulatory functions. Polydatin shows favorable cytotoxic effects against various tumor cell lines, including cervical cancer cells, liver cancer cells, and nasopharyngeal carcinoma cells .
Assay Types